Buy GHB (Gamma-Hydroxybutyric Acid)
€ 125,00
Buy Pure Gamma-Hydroxybutyric Acid Sodium Salt for Neuroscience & Sleep Research
Unlock the mysteries of GABA-B modulation and endogenous sedation with Nova Chemics GHB, the benchmark in gamma-hydroxybutyric acid sodium salt purity—crafted for labs exploring narcolepsy, addiction pathways, and neuroprotection. Every gram delivers 99.9%+ purity via HPLC, GC-MS, FTIR, and NMR, free from GBL, 1,4-butanediol, or industrial contaminants. Whether modeling sleep architecture, dopamine rebound, or forensic toxicology, our crystalline GHB ensures instant solubility, precise dosing, and publication-grade reproducibility.
Synthesized under cGMP-aligned conditions, this fine white hygroscopic powder dissolves in <5 seconds in water. In research models: onset 5–15 min (oral/IP), peak 30–60 min, duration 2–4 hours—ideal for GHB receptor binding, cataplexy simulation, or withdrawal phenotyping. First isolated in 1874, GHB’s dual role as neurotransmitter and DEA Schedule I drug (therapeutic Schedule III as Xyrem®) makes it a 2025 cornerstone—our powder powers that science.
What Is GHB?
The Body’s Own Sleep Switch
Gamma-hydroxybutyric acid (GHB) is a CNS depressant and GABA metabolite, naturally occurring in millimolar brain concentrations. It binds GHB receptors (GPCR) and GABA-B (weakly), triggering delta-wave sleep, GH release, and euphoric sedation. Clinically, sodium oxybate (GHB-Na) treats narcolepsy-cataplexy at 4.5–9 g/night. Illicitly, it’s a date rape drug due to amnesia and muscle relaxation. Our research-grade GHB isolates the sodium salt—non-hygroscopic when sealed, pH-neutral in solution, and free from GBL conversion risks.
Key Features: Lab-Crafted for Precision Sleep Science
- Snow-White Powder: <20 μm, non-clumping, 99.9%+ GHB-Na
- Instant Solubility: >500 mg/mL in water, pH 7.0–7.5
- Rapid Onset: Oral/IP 5–15 min; IV <2 min
- Short Half-Life: 30–50 min, ideal for acute studies
- Clean Profile: Zero GBL, BDO, or ethanol
Why Nova Chemics? We don’t repackage industrial cleaners. We synthesize from BDO + NaOH under inert atmosphere, triple-recrystallize, and validate with chiral GC-MS—delivering the same material used in Jazz Pharmaceuticals trials.
Product Specifications – Batch NC-GHB-2025-11E
| Attribute | Specification |
|---|---|
| Chemical Name | Sodium 4-hydroxybutanoate |
| CAS Number | 502-85-2 |
| Purity | 99.9%+ (HPLC/GC-MS/NMR) |
| Appearance | Fine white powder (<20 μm) |
| Solubility | >500 mg/mL in water; <1 mg/mL in ethanol |
| Melting Point | 142–146°C (decomp.) |
| Molecular Weight | 126.09 g/mol |
| pKa | 4.72 |
| LogP | -0.6 |
| GHB Receptor Ki | ~0.1–1 μM |
| GABA-B Ki | ~100 μM |
Download COA → NC-GHB-2025-11E Lab Report
Reagent Test Guide
| Reagent | Expected Reaction |
|---|---|
| Marquis | No color |
| Mecke | No reaction |
| Mandelin | No color |
| Liebermann | Yellow → orange |
| Froehde | No reaction |
Includes 5-reagent kit + fentanyl strips.
Usage Instructions: The Sedation Protocol
- Reconstitution:
- Oral/IP: 10–100 mg/mL in 0.9% saline (pH 7.2)
- IV: Filter 0.22 μm, use within 1h
- Dosing (Rodent Models):
- Sleep Induction: 100–300 mg/kg IP
- Cataplexy: 50–150 mg/kg
- Withdrawal: 400–800 mg/kg/day
- Administration:
- Oral gavage: Most translational
- IP: Faster onset
- Monitoring: EEG (delta power), core temp, respiration
Free “Sedation Protocol” PDF: Includes dose-response curves, GHB receptor binding, sleep staging, and IRB templates.
Packaging & Storage
- Packaging: Amber vials, PTFE caps, silica gel, mylar vacuum seal, neutral box (“sodium salt reagent”)
- Storage:
- Short-term: 2–8°C, desiccated
- Long-term: -20°C, stable >60 months
- Solution: Use immediately; unstable >2h at RT
Safety: Handle with Extreme Care
GHB causes respiratory depression, coma at >50 mg/kg, addiction with chronic use. LD₅₀ (rat): ~1,700 mg/kg. Contraindications: CNS depressants, succinic semialdehyde dehydrogenase deficiency. Use Class II hood, nitrile gloves, eye protection. Neutralize spills with water flush. Includes flumazenil card (GABA-B reversal).
Shipping: Stealth & Speed
- Hubs: EU, US
- Timelines: EU/UK 1–3 days; US/CA 2–4 days; Global 4–7 days
- Stealth: 99.2% success, 100% reship
- Free over €200
How to Buy: One-Click Discretion
- Select → Cart → Checkout
- Pay: Crypto (10% off)
- Ship <24h
Bulk: 50g+ = wholesale + express
Our Services
- 24/7 Live Support (@NovaSupport24)
- Product Replacement – Free if purity <99.9%
- Authenticity Guarantee – Refund if COA fails
- Technical Consultation – Free sleep study design
- Complaint Handling – <12h
Legal Considerations
DEA Schedule I (US), Class C (UK), Schedule I (Canada). Therapeutic exception: Xyrem® (Schedule III). Legal only with DEA license, import permits. Sold strictly for licensed research. Buyer affirms institutional compliance.

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