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Description

Buy Pure Gamma-Hydroxybutyric Acid Sodium Salt for Neuroscience & Sleep Research

Unlock the mysteries of GABA-B modulation and endogenous sedation with Nova Chemics GHB, the benchmark in gamma-hydroxybutyric acid sodium salt purity—crafted for labs exploring narcolepsy, addiction pathways, and neuroprotection. Every gram delivers 99.9%+ purity via HPLC, GC-MS, FTIR, and NMR, free from GBL, 1,4-butanediol, or industrial contaminants. Whether modeling sleep architecture, dopamine rebound, or forensic toxicology, our crystalline GHB ensures instant solubility, precise dosing, and publication-grade reproducibility.

Synthesized under cGMP-aligned conditions, this fine white hygroscopic powder dissolves in <5 seconds in water. In research models: onset 5–15 min (oral/IP), peak 30–60 min, duration 2–4 hours—ideal for GHB receptor binding, cataplexy simulation, or withdrawal phenotyping. First isolated in 1874, GHB’s dual role as neurotransmitter and DEA Schedule I drug (therapeutic Schedule III as Xyrem®) makes it a 2025 cornerstone—our powder powers that science.


What Is GHB?

The Body’s Own Sleep Switch

Gamma-hydroxybutyric acid (GHB) is a CNS depressant and GABA metabolite, naturally occurring in millimolar brain concentrations. It binds GHB receptors (GPCR) and GABA-B (weakly), triggering delta-wave sleep, GH release, and euphoric sedation. Clinically, sodium oxybate (GHB-Na) treats narcolepsy-cataplexy at 4.5–9 g/night. Illicitly, it’s a date rape drug due to amnesia and muscle relaxation. Our research-grade GHB isolates the sodium saltnon-hygroscopic when sealed, pH-neutral in solution, and free from GBL conversion risks.


Key Features: Lab-Crafted for Precision Sleep Science

  • Snow-White Powder: <20 μm, non-clumping, 99.9%+ GHB-Na
  • Instant Solubility: >500 mg/mL in water, pH 7.0–7.5
  • Rapid Onset: Oral/IP 5–15 min; IV <2 min
  • Short Half-Life: 30–50 min, ideal for acute studies
  • Clean Profile: Zero GBL, BDO, or ethanol

Why Nova Chemics? We don’t repackage industrial cleaners. We synthesize from BDO + NaOH under inert atmosphere, triple-recrystallize, and validate with chiral GC-MS—delivering the same material used in Jazz Pharmaceuticals trials.


Product Specifications – Batch NC-GHB-2025-11E 

Attribute Specification
Chemical Name Sodium 4-hydroxybutanoate
CAS Number 502-85-2
Purity 99.9%+ (HPLC/GC-MS/NMR)
Appearance Fine white powder (<20 μm)
Solubility >500 mg/mL in water; <1 mg/mL in ethanol
Melting Point 142–146°C (decomp.)
Molecular Weight 126.09 g/mol
pKa 4.72
LogP -0.6
GHB Receptor Ki ~0.1–1 μM
GABA-B Ki ~100 μM

Download COANC-GHB-2025-11E Lab Report


Reagent Test Guide

Reagent Expected Reaction
Marquis No color
Mecke No reaction
Mandelin No color
Liebermann Yellow → orange
Froehde No reaction

Includes 5-reagent kit + fentanyl strips.


Usage Instructions: The Sedation Protocol

  1. Reconstitution:
    • Oral/IP: 10–100 mg/mL in 0.9% saline (pH 7.2)
    • IV: Filter 0.22 μm, use within 1h
  2. Dosing (Rodent Models):
    • Sleep Induction: 100–300 mg/kg IP
    • Cataplexy: 50–150 mg/kg
    • Withdrawal: 400–800 mg/kg/day
  3. Administration:
    • Oral gavage: Most translational
    • IP: Faster onset
  4. Monitoring: EEG (delta power), core temp, respiration

Free “Sedation Protocol” PDF: Includes dose-response curves, GHB receptor binding, sleep staging, and IRB templates.


Packaging & Storage

  • Packaging: Amber vials, PTFE caps, silica gel, mylar vacuum seal, neutral box (“sodium salt reagent”)
  • Storage:
    • Short-term: 2–8°C, desiccated
    • Long-term: -20°C, stable >60 months
    • Solution: Use immediately; unstable >2h at RT

Safety: Handle with Extreme Care

GHB causes respiratory depression, coma at >50 mg/kg, addiction with chronic use. LD₅₀ (rat): ~1,700 mg/kg. Contraindications: CNS depressants, succinic semialdehyde dehydrogenase deficiency. Use Class II hood, nitrile gloves, eye protection. Neutralize spills with water flush. Includes flumazenil card (GABA-B reversal).


Shipping: Stealth & Speed

  • Hubs: EU, US
  • Timelines: EU/UK 1–3 days; US/CA 2–4 days; Global 4–7 days
  • Stealth: 99.2% success, 100% reship
  • Free over €200

How to Buy: One-Click Discretion

  1. Select → Cart → Checkout
  2. Pay: Crypto (10% off)
  3. Ship <24h

Bulk: 50g+ = wholesale + express


Our Services

  • 24/7 Live Support (@NovaSupport24)
  • Product Replacement – Free if purity <99.9%
  • Authenticity Guarantee – Refund if COA fails
  • Technical Consultation – Free sleep study design
  • Complaint Handling – <12h

Legal Considerations

DEA Schedule I (US), Class C (UK), Schedule I (Canada). Therapeutic exception: Xyrem® (Schedule III). Legal only with DEA license, import permits. Sold strictly for licensed research. Buyer affirms institutional compliance.

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